Defender for Endpoint (DfE) – Windows

What is happening:

Currently all UF Pediatrics IT managed machines with Windows operating systems are being targeted for migration on the 12th of March, 2024 (Tuesday) @ 2:00AM. This update WILL require a restart. Please see below for options on installing the update before the deadline or waiting until the deadline for the forced installation.

What to do:

Option 1 – Self Initiated Installation:

If you would like to perform the installation before the deadline. The steps to do so are below:

  1. Open Software Center from your desktop.
  2. Select the “Trend Apex One – Uninstall” application and then select “INSTALL” in the bottom right of Software Center.
  3. This will uninstall Trend and produce a 2-hour countdown prompt. Select restart to finish the installation.

Option 2 – Forced Installation at Deadline:

On the deadline, 12th of March, 2024 (Tuesday) @ 2:00AM your machine will uninstall Trend Micro antivirus and restart. 


  • Trend Micro will be removed from targeted systems.
  • Microsoft Defender for Endpoint will be activated.

Verify Defender for Endpoint activation:

Follow the steps below to verify that Microsoft Defender Antivirus has been activated.

  1. Open the Start Menu and type “security”. Then open “Windows Security”.
  2. In Windows Security, open “Virus & Threat Protection”.
  3. On the right side of Virus & Threat Protection, select “Manage Providers”.
  4.  On Security Providers page, Microsoft Defender Antivirus should now show as turned on.
  5. It is possible that Microsoft Defender may not show up right away as the service can take some time to initialize. If you do not see it close Windows Security, and wait a few minutes then perform the verification steps again.